Proteomics Software | Data-Independent Acquisition | DIA Proteomics

Software

Spectronaut®

The gold standard for DIA proteomics analysis

Thanks to deep-learning augmented peptide identification, you can now find more precursors and proteins in your samples than ever before. We have further broadened our support for the latest mass spectrometry data acquisition technologies, and provide new ways to quickly and thoroughly analyze data.

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      Spectronaut® is a commercial software package aimed at analyzing data-independent acquisition (DIA) proteomics experiments. Spectronaut® can quantitatively profile 100s to several 1,000s of proteins in one experiment. Large experiments with several conditions and replicates consisting of up to 10,000s of LC-MS runs can be analyzed.

      Features:

      1. Vendor Independent
      2. Usability
      3. Complete Workflow
      4. Performance and Scalability
      5. Versatility and Flexibility

       

      Check out what’s new in Spectronaut®19.

      Supported Instruments

       

      • Thermo Scientific™ Orbitrap Astral
      • Thermo Scientific™ Orbitrap Exploris™ 480
      • Thermo Scientific™ Q Exactive™ Series
      • Thermo Scientific™ Orbitrap Fusion™ Series
      • Bruker timsTOF™ Pro series and timsTOF HT
      • Bruker timsTOF™ SCP and timsTOF Ultra series
      • Bruker timsTOF™ Flex Bruker Impact II
      • SCIEX ZenoTOF 7600 System
      • SCIEX TripleTOF® Series
      • Waters Xevo® G2-XS
      Supported Methods

       

      • HRM™
      • dia-PASEF®
      • SWATH™
      • Zeno SWATH
      • BoxCar DIA
      • SONAR™
      • WiSIM-DIA

       

      Methods should acquire MS1 and MS2 or MS2 only scans. The cycle time of the method should be in the range of 1-3 seconds depending on your average peak width. Fractionation, including gas-phase fractionation, is supported.

      Recommended System Requirements*

       

      • Windows 10 x64 / Windows Server 2016 or later
      • Intel or AMD CPU with 4 cores or more
      • 2 TB of free hard drive space or more (2x data set size)
      • 16 GB of memory or more (1 precursor in 1 run amounts to ~0.5 KB of RAM)

       

      *for a library-free experiment with 200 DIA runs and typical search space settings

      If you are interested in ordering one of our software, please submit a request form or contact us. Our team will review your inquiry and get back to you within 5 working days.

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        New: Spectronaut® 19

        Unlock Your Data's True Story

        New: Spectronaut® 19

        Unlock Your Data's True Story

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