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Why is Targeted Protein Degradation a Hot Topic in Drug Development?

Targeted protein degradation is an exciting new strategy in drug development with applications in a wide range of diseases, from cancer to neurodegeneration to autoimmune conditions.

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May 2023
Mass Spectrometry Proteomics is Key to Realizing the Potential of Targeted Protein Degraders

Targeted protein degradation is an exciting new strategy in drug development with applications in a wide range of diseases, from cancer to neurodegeneration to autoimmune condition [...]

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April 2023
What Do Advances in Structural Proteomics Mean for Drug Development?

During drug development, understanding how a compound binds to its target(s) is an important step in lead selection and optimization. A thorough dissection of drug–protein intera [...]

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February 2023
Why is Targeted Protein Degradation a Hot Topic in Drug Development?

Targeted protein degradation is an exciting new drug discovery strategy that promises to reach previously undruggable proteins, expanding the clinically useful range of the proteom [...]

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January 2023
Proteomics Simplified: Library-free Analysis Takes DIA Mainstream

Once an exciting but niche technology, DIA mass spectrometry has transformed proteomics. In his new article, Biognosys' CTO, Lukas Reiter, takes us through the journey to this poin [...]

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January 2023
Immunopeptidome Profiling Unleashes the Power of Personalized Immunotherapy

Immunopeptidome profiling at this scale provides a detailed snapshot of what the immune system reacts to within a particular tissue. This has important implications for understandi [...]

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December 2022
Know Your Target: Why Structural Proteomics Is the Best Tool for Drug Target Validation

Mass spectrometry-based structural proteomics provides deep insights into drug-protein interactions for drug target identification and validation to de-risk your drug development p [...]

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