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Expanding horizons: Maximizing the potential of targeted protein degradation

Targeted protein degradation is an innovative new therapeutic approach that works by completely removing disease-associated proteins instead of inhibiting them. This approach can be used to develop more specific therapeutics with higher success rates that can target previously “undruggable” proteins.

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January 2025
Decoding Protein Modifications with Spectronaut: Normalizing Background Proteins for Accurate PTM Quantification

Understanding post-translational modifications (PTMs) is crucial in unraveling the complexities of protein function, particularly their role in health, disease, and therapeutic int [...]

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April 2024
Why you should be using MS-based proteomics in hematology

Targeted protein degradation is an innovative new therapeutic approach that works by completely removing disease-associated proteins instead of inhibiting them. This approach can b [...]

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February 2024
Expanding horizons: Maximizing the potential of targeted protein degradation

Targeted protein degradation is an innovative new therapeutic approach that works by completely removing disease-associated proteins instead of inhibiting them. This approach can b [...]

Read more
December 2023
5 Reasons Why DIA Can Elevate Your Proteomics Research

Data-independent acquisition (DIA) allows for unbiased, robust quantification over thousands of samples, ultimately providing deeper proteome coverage than data-dependent acquisiti [...]

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August 2023
Exosomes Made Easy: A Novel High-throughput Mass Spectrometry Proteomics Workflow for Extracellular Vesicle Analysis

In this article, we explore how recent advances in mass spectrometry (MS) proteomics can now offer a solution to these challenges, providing robust, scalable, deep analysis of the [...]

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July 2023
Extracellular Vesicles: How Understanding the Body’s ‘Secret Messengers’ Sheds Light on Disease

2023 marks the fortieth anniversary of the discovery of exosomes – tiny extracellular vesicles that are increasingly being recognized as playing an important role in health and d [...]

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