Ready to use workflows for isobaric label-based quantification
More immunopeptides identified with Kuiper
Powerful search engines working together
SpectroMine offers a seamless, vendor-neutral DDA proteomics solution that delivers deep proteome analysis. Its intuitive interface and automated workflows streamline spectral library creation, PTM analysis, and both labelled and label-free quantification with minimal setup. Optimised for high throughput and reproducibility – and fully compatible with all major mass spectrometers – SpectroMine empowers researchers to generate robust, high-confidence data faster than ever.
Questions? Jump to FAQ Section
Analyze DDA data from any major mass spectrometry vendor and most popular methods.
The all‑new Kuiper search engine takes peptidomics searches to new depths and record speeds.
Our team spans the globe enabling fast response whenever you need us.
SpectroMine supports mass spectrometers from Thermo Scientific™, Sciex, Bruker and Waters.
The specific supported models are:
SpectroMine performs two main tasks with MS run files as input: searching, and quantifying isobaric labeled and label-free DDA experiment samples.
SpectroMine is available for Windows and Linux operating systems (operated via command line).
Detailed, recommend specifications:
We offer licensing solutions designed to suit your needs. Please reach out via our contact form or email us at support@biognosys.com for more information.
Kuiper is specifically designed for peptidomics data, offering unprecedented speed and deeper identification coverage — unlocking new possibilities in the field of immunopeptidomics.
With newly added Linux support, enhanced visualizations, and seamless alignment between the Pulsar search engine and Spectronaut®, SpectroMine 5 takes your DDA analysis to the next level.
The all-new Kuiper search engine in SpectroMine 5 truly breaks new ground for analysis of immunopeptides for DDA proteomics, offering 20% more HLA type I peptide IDs on average (n=16) with >80% reduced analysis time (n=16) compared to SpectroMine 4.
Unlike other engines which are optimized for traditional tryptic peptides, Kuiper is built to deliver fast, reliable and deep coverage of the most challenging search spaces.
SpectroMine 5 now features support for Linux OS. Deploy your DDA workflow in the cloud or High Performance Computing (HPC) via Linux environments with more flexible deployment options.
Linux’s open-source architecture and powerful command line tooling allows for scalable performance and seamless automation, accelerating analyses without sacrificing reliability. All the analysis results can be conveniently loaded and reviewed in Windows based SpectroMine viewers. Discover high-throughput DDA analysis with SpectroMine 5.
Introducing PTM Probing Search mode, powered by the all-new Kuiper search engine. Dive deeper into your samples by simultaneously screening dozens of PTMs in a single pass, uncovering unexpected modifications and boosting your identification rates even in challenging search spaces of unspecific digestion. With Kuiper’s lightning-fast indexing — you’ll reveal comprehensive proteomic landscapes — no compromise, no blind spots. Add PTM Probing Search into your workflow to explore more biology, faster than ever before.
I have been thoroughly impressed by the capabilities of SpectroMine, particularly in the context of MS-based quantitative proteomics for host cell protein monitoring.
SpectroMine is Biognosys’ powerful and user–friendly solution for DDA proteomics. SpectroMine comes with significantly increased processing speed and new functionalities for specialized workflows such as PTM analysis and immunopeptidomics. Take advantage of the most powerful search engine for isobaric labelling quantification with support for the latest acquisition methods and labelling reagents.
Biognosys offers a complimentary 30–day trial of SpectroMine, including full access to all features, training materials, and expert support. During the trial, you can explore key workflows using your own DDA data, with guidance available through video tutorials and a dedicated consultation session.
To request a trial, simply complete the “Start a free trial” form – our team will be in touch with next steps.
Our support team is available at support@biognosys.com.
If you need further assistance, please contact us at support@biognosys.com.
For consultations or help with specific software questions, kindly include details about your analysis, workflow steps, and any relevant error messages or logs to help us provide efficient and targeted support.
Our complete suite of proteomics kits and software solutions empowers researchers to perform cutting-edge proteomics in-house.
The gold–standard scalable software package for comprehensive analysis of data–independent acquisition (DIA) proteomics experiments.
Simplify Your Targeted Proteomics Analysis.
For up to 500 injections – Retention time normalization kit for time-resolved mass spectrometry.
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