Shotgun proteomics, also known as data-dependent acquisition (DDA), plays an important role in the generation of spectral libraries, qualitative proteome analysis, and the identification of post-translational modifications. In addition, recent innovations in isobaric labeling quantification, with the introduction of novel tags and wider multiplexing options, add accurate quantification of the proteome and widen the applications of shotgun proteomics for quantitative analysis.
SpectroMine™ can search DDA, DIA, and PRM with MS1 information.
SpectroMine™ can search and quantify DDA runs from isobaric-labeled experiments using labels such as TMT, EASI-tag, and iTRAQ.
MS2 and SPS-MS3 methods are supported. All ion trap resolutions are supported. SpectroMine™ supports neutral loss-based fragmentation label methods (such as EASI-tag).
Recommended System Requirements
Windows 10 x64
Intel or AMD CPU with 4 cores or more
2 TB of hard drive space or more (2x data set size)
16 GB of memory space or more
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