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Targeted proteomics software for the analysis of PRM and MRM measurements from various MS platforms.

Now available: SpectroDive 8 supports library generation from DDA results and subsequent panel generation for data acquisition with Multiple or Parallel Reaction Monitoring (MRM and PRM) workflows.

Smartest peak picking algorithms enable extremely fast analysis of large datasets.

Please take a look at our General Software License.


Product number: Sw-3002

SpectroDive™ is Biognosys’ proprietary software for automated MS method set-up, signal processing and analysis of MRM and PRM experiments. Contact us for a FREE TRIAL!

SpectroDive™ Features:

  • Library generation from DDA results
  • MRM / PRM panel generation from library
  • Automated MS method set-up, signal processing, and analysis
  • Integrated iRT calibration
  • Powerful peak scoring
  • Immediate and intuitive data visualization
  • Customized reporting
  • Fully automated quality control

Please contact us for support.

Supported Instruments


  • Thermo Scientific™ TSQ™ Series (Vantage, Quantum, Quantiva)
  • AB SCIEX Triple Quad 5500
  • Agilent 6400 Series


  • Thermo Scientific™ Q Exactive™ Series
  • Thermo Scientific™ Orbitrap Fusion™ Series
  • AB SCIEX TripleTOF® Series (5600, 5600+, 6600)

System Requirements

Windows 7 x64
CPU Intel® Core™, 2.7 GHz (quad core)
HDD 50 GB free space
Memory 4 GB
Software .NET 4.7.

Windows 7 x64 or higher
CPU Intel® Core™ i7 4770, 3.4 GHz (octa core) or more
HDD 50 GB free space (SSD)
Memory 16 GB or more
Software .NET 4.7 or higher.

How to Order

Simply Add to Cart and proceed to checkout. Our team will review your inquiry and get back to you within 1 working day.


Please contact us for support.

Visit Science Hub to access all scientific and technical content (publications, videos, application notes, posters and more) related to Biognosys technology, products and services.

Peer-Reviewed Papers

  1. Zanetti F, Sewer A, Scotti E, Titz B, Schlage WK, Leroy P, et al. Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens. Food Chem Toxicol. 2018; 115:148-169.
  2. Iskandar AR, Martin F, Leroy P, Schlage WK, Mathis C, et al. Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment. Food Chem Toxicol. 2018 Mar 1;115:109-126.
  3. Manes NP, Nita-Lazar A. Application of targeted mass spectrometry in bottom-up proteomics for systems biology research. J Proteomics. 2018 Feb 13.
  4. Uzozie AC, Selevsek N, Wahlander A, Nanni P, Grossmann J, Weber A, Buffoli F, Marra G. Targeted Proteomics for Multiplexed Verification of Markers of Colorectal Tumorigenesis. Mol Cell Proteomics. 2017; 16(3):407-427.
  5. Iskandar AR, Titz B, Sewer A, Leroy P, Schneider T, Zanett F, et al. Systems toxicology meta-analysis of in vitro assessment studies. Toxicol. Res., 2017, 6, 631-653.
  6. Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, et al. The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR. J Cell Biol. 2016; 215(4):543-558.
  7. Ori A, Iskar M, Buczak K, Kastritis P, Parca L, Andrés-Pons A, Singer S, Bork P, Beck M. Spatiotemporal variation of mammalian protein complex stoichiometries. Genome Biol. 2016; 17(1):47.
  8. Cantonwine DE, Zhang Z, Rosenblatt K, Goudy KS, Doss RC, Ezrin AM, Page G, Brohman B, Mcelrath TF. Evaluation of proteomic biomarkers associated with circulating microparticles as an effective means to stratify the risk of spontaneous preterm birth. Am J Obstet Gynecol. 2016 Feb 10. doi: 10.1016/j.ajog.2016.02.005.
  9. Poli M, Ori A, Child T, Jaroudi S, Spath K, Beck M, Wells D. Characterization and quantification of proteins secreted by single human embryos prior to implantation. EMBO Mol Med. 2015 Oct 15.
  10. Kiseleva OI, Romashova YA, Moskaleva NE, Petushkova NA, Teryaeva NB, Belyaev AY, Lisitsa AV. Plasma preparation to measure FDA-approved protein markers by selected reaction monitoring. Clin Transl Med. 2015; 4(1):32.
  11. von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, Beck M. In situ structural analysis of the human nuclear pore complex. Nature. 2015; 526(7571):140-3. 
  12. Ori A, Toyama BH, Harris MS, Bock T, Iskar M, et al. Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats. Cell Systems. 2015; 1(3): 224–237.
  13. Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, et al. Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold. J Cell Biol. 2015; 208(3):283-97. 

If we forgot to include your publication that uses our technology, please don’t hesitate to let us know at

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Which Vendors are supported by SpectroDive?

SpectroDive supports Sciex, Agilent and Thermo instruments capable of MRM or PRM. For Thermo the method exported can directly be used in the instrument method set up without any further modifications. 

What measurement modes are supported?

SpectroDive supports MRM and PRM measurements for all the instruments capable of acquiring in one of the modes. 

How are the differential abundant candidates in the Post Analysis Perspective calculated?

To determine the proteins differentially abundant between different conditions SpectroDive is performing a one sample t-test on the log ratios of all features between all conditions. 

I do not like the default settings where can I change them?

The Biognosys factory settings or also called default settings have proven to be suitable for the majority of the experimental setup. Yet, sometimes individual settings are necessary. To perform data analysis using user-defined settings there are two options available. Option 1: the settings are modified in the Review Perspective when setting up the experiment. Option 2: In the Settings Perspective the settings are modified and stored in a separate settings schema. 

I want to subject the data generated in SpectroDive to third-party analysis tools; how can I do this?

The Report Perspective is designed in a way that all accessible information can be exported. For certain downstream analysis tools, a reporting schema can be created based on the information needed. If you need help establishing a schema do not hesitate to contact us at

Please contact us for support.


Let us help you do great proteomics!

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