Spectronaut® 16 brings users the ability to identify and quantify more from their DIA data than ever before. With an improved directDIA workflow, new deep learning scores, and an enhanced user experience, DIA data has never been this meaningful.
“With Spectronaut 16, our users can achieve deeper proteome coverage than with any other solution on the market, while benefiting from a seamless user experience.”
Lukas Reiter, Ph.D., CTO of Biognosys
Spectronaut 16 offers an unprecedented boost in identifications. Here we show a comparison with Spectronaut 15.
These improvements apply to both library-based and library-free workflows. Identification numbers are also consistently higher across all instrument vendors, ensuring significant improvements for all Spectronaut users.
To guarantee that you can trust your Spectronaut data, the software’s run-wise protein FDR control makes sure that your results are accurate every time, without compromising on the number of identifications.
Spectronaut 16 consistently outperforms other solutions when analyzing high-throughput DIA data.
When testing Spectronaut 16 against exemplary short-gradient DIA data1,2 our results demonstrate that Spectronaut 16 identifies more precursors and more protein groups than other solutions on the market. Comparable results were observed for FAIMS data.
Blood plasma is an important cornerstone in detecting and monitoring the progression of many diseases.
With Spectronaut 16, analyzing plasma data is more accurate than before.
Spectronaut 16 is not only able to identify more protein groups in plasma than Spectronaut 15, but also recovers significantly more true candidates when measuring mixed proteome samples spiked in different amounts (Human depleted Plasma 1:1, E. coli 1:0.4, S. cerevisiae 1:1.3).
With Spectronaut 16 it is easier than ever to work with enriched directDIA data. This powerful workflow is now easily accessible with the click of a button to make your Hybrid directDIA analysis the smoothest yet.
In this tutorial, Monika Puchalska from our Product Support team demonstrates how easy it is to set up your enriched directDIA analysis in Spectronaut.
In addition, Monika provides an overview of the new visualization options in Spectronaut 16 that help you get insights from your DIA analysis results even faster.
Spectronaut® is a commercial software package aimed at analyzing data-independent acquisition (DIA) proteomics experiments. Spectronaut® can quantitatively[...]READ MORE
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Monika Puchalska from our Product Support team demonstrates how to set up your DIA analysis in Spectronaut 16 using Biognosys’ directDIA workflow with a streamlined library[...]READ MORE
Highlights include the launch of Spectronaut® 16, which has undergone one of its most transformative upgrades to date, and innovations to Biognosys’ proprietary TrueTarget™[...]READ MORE