Publications

Pharmacokinetic Analysis of Omomyc Shows Lasting Structural Integrity and Long Terminal Half-Life in Tumor Tissue

Beaulieu M-E, Martínez-Martín S et al. Cancers. Blocking MYC is the holy grail for human cancer treatment. However, the development of clinically viable [...]

Publications

Global, in Situ Analysis of the Structural Proteome in Individuals with Parkinson’s Disease to Identify a New Class of Biomarker

Marie-Therese Mackmull et al. Nature Communications. This publication on Nature Structural and Molecular Biology is the result of the collaboration betwee [...]

Publications

Date: 16/07/2022

Compounds Activating VCP D1 ATPase Enhance Both Autophagic and Proteasomal Neurotoxic Protein Clearance

Wrobel L. et al. Nature Communications Enhancing the removal of aggregate-prone toxic proteins is a rational therapeutic strategy for a number of neurodeg [...]

Publications

Date: 24/03/2022

Biomarker Candidates for Tumors Identified from Deep-profiled Plasma Stem Predominantly from the Low Abundant Area

Tognetti et al. Journal of Proteome Research. The plasma proteome has the potential to enable a holistic analysis of the health state of an individual. Ho [...]

Publications

Date: 22/02/2022

The Essentials of Multiomics

John L Marshall et al. The Oncologist. Within the last decade, the science of molecular testing has evolved from single gene and single protein analysis t [...]

Publications

Date: 25/12/2021

Mechanistic Insights into a CDK9 Inhibitor Via Orthogonal Proteomics Methods

Hendricks et al. American Chemical Society's Chemical Biology Journal. The publication shows how orthogonal proteomics approaches can be applied to quanti [...]