We have prepared two video tutorials on spectral library generation and an application note describing the interference correction algorithm that is implemented in the Spectronaut™ software.
Video tutorials will show you how to make a high quality spectral library in Spectronaut™ using either Proteome Discoverer 1.4 or MaxQuant 1.5 (the videos are uploaded on our Youtube channel). If you look closely you can also see some of the new features of the Spectronaut™ 7 that will be released in a couple of weeks.
In the application note we show an intuitive new algorithm in Spectronaut™ that automatically recognizes interferences and corrects them for quantitation. The results are greatly improved quantitation precision (i.e. reduced coefficients of variation), the most important factor in label free quantitative proteomics.