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Proteomics MS monitoring software for DDA, DIA, PRM, and MRM measurements from various MS platforms.

QuiC 2.0 is now available (for more information click here).

Generates liquid chromatography (LC) and mass spectrometer (MS) QC readouts in near real-time from raw files of various LC-MS vendors across various workflows (SRM/MRM, PRM, DIA, DDA).

Requires Biognosys iRT Kit or HRM Calibration Kit to enable automated, fast and accurate QC monitoring of your data sets.

Please take a look at our General Software License.


Annual Single System License

Product number: Sw-3003



In stock

LC-MS based proteomics has become the method of choice for the comprehensive identification and quantification of proteins over large sample sets. Robust and accurate quality controls (QC) during data acquisition and in between instrument maintenance are essential to ensure that high-quality data with low systematic errors are collected.

QuiC is a simple tool that generates QC readouts in near real-time which are of tremendous help for the LC-MS expert but can be interpreted also by non-mass spec experts. QuiC can be set up to regularly check folders for new raw files which can be used to continuously monitor instrument performance. A multitude of readouts are provided, the most important ones are based on the iRT peptides. For DIA and DDA additional readouts for a background proteome are also provided. This tool enables users to judge data quality and intervene as needed to prevent sample loss, LC-MS downtime, and low data quality.

Please contact us for support.

Supported Workflows

  • Selected or Multiple Reaction Monitoring (SRM/MRM)
  • Parallel reaction monitoring (PRM)
  • Data-independent acquisition (DIA) or SWATH
  • Data-dependent acquisition (DDA)


Supported Instruments

  • Thermo Scientific™ Orbitrap Exploris™ 480
  • Thermo Scientific™ Orbitrap Eclipse™ Tribrid™
  • Thermo Scientific™ Q Exactive™ Series
  • Thermo Scientific™ Orbitrap Fusion™ Series
  • Thermo Scientific™ Orbitrap Elite™
  • Thermo Scientific™ TSQ Series™
  • SCIEX TripleTOF® Series
  • SCIEX Triple Quad Series
  • SCIEX QTRAP Series
  • SCIEX API Series
  • Agilent 6400 Series
  • Bruker Impact II
  • Bruker timsTOF™ and timsTOF™ Pro (without ion mobility)
  • Waters Xevo® G2-XS
  • Waters Xevo® TQ-S


Minimum System Requirements

  • Windows 7 x64
  • Intel Core™ CPU 2.7 GHz (quad-core) or similar
  • 500 GB of free HDD space
  • 16 GB of RAM memory
  • .NET Framework 4.7


How to Order

Simply Add to Cart and proceed to checkout. Our team will review your inquiry and get back to you within 5 working days.

Please contact us for support.


Let us help you do great proteomics!

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