Validation of CRISPR Gene Knockouts in U2OS Cell Lines with DIA MS-Based Proteomics - Biognosys

Validation of CRISPR Gene Knockouts in U2OS Cell Lines with DIA MS-Based Proteomics

Case Studies

CRISPR-Cas9 is an essential tool for gene editing in cellular systems with routine applications in functional screening, target validation and identification as well as generation of disease models. High-throughput confirmation of KOs at protein level is often time-consuming and cost-intensive. In this study, we demonstrated the utility of a quantitative proteomic approach to concurrently validate CRISPR KO results and to monitor their functional impacts in cells.

Back to Resources overview

Helpdesk

Access our knowledge base with relevant resources and guiding information.

Contact

    Close banner

    Biognosys at #AACR23

    8 Posters & Booth #319

    Biognosys Will Be at the AACR Annual Meeting 2023

    Eight Poster Presentations and Exhibition Booth #319

    Learn More