SpectroDive™ 12: Unleash the Power of Precision

SpectroDive™ 12: Unleash the Power of Precision

Launch Pages

SpectroDive™ 12 delivers breakthrough performance for targeted workflows. New features, including in silico panel creation, custom assignment of labels, support for multiple calibration curves, and improved library generation make your targeted proteomics workflows more productive.

 

 

 

“New SpectroDive™12, with its robust peak-picking algorithm and a novel in-silico panel generation, enables us to quickly design and analyze large-scale immunopeptidomics and plasma proteomics target validation assays.”

 

Simonas Savickas, PhD, Sr. Scientist at Biognosys

Feature Overview:

 

  • Custom Label Assignment: Take control of your candidates with customizable label assignments and improved visualizations for residue-level resolution.

 

  • Multiple Calibration Curves: The calibration curve feature is now enhanced to support multiple curves giving you the flexibility to quantitate more targets.

 

  • Improved Library Generation: Enhancements to Pulsar improve library generation, supporting empirical panel generation with more identifications.

 

SpectroDive 12 Release Notes

Streamline Quantification with AI-Generated Panels

Accelerate your targeted proteomics research with deep learning-based in-silico panel development in SpectroDive12.

Our built-in model optimizes for iRT, fragmentation, and ion mobility to generate predicted panels. Compared to traditional assay-based panels, this approach drastically reduces the time needed to create high-quality panels from hours to minutes.

In silico panel generation in SpectroDive 12 delivers similar quality and reliable results to traditional assay-based panels, allowing researchers to focus more on discovery and less on preparation.

Flexible Quantification with Multiple Calibration Curves

Using calibration curves in targeted proteomics analysis allows you to calculate sensitivity, quantification ranges, and measurement precision accurately.

Support for multiple calibration curves in SpectroDive 12 makes absolute quantification more flexible than ever. This feature allows you to use calibration curves, generated in separate analyses. You now have the flexibility to apply the best curve to your panel. In turn this can be used to calculate linear ranges, limits of detection and quantify targets.

Increase Flexibility and Throughput with Custom Assigned Labels

SpectroDive 12 now supports custom assignment of labels for label location and custom chemistry. This feature allows you to localize labels to specific residues on each peptide target.

Improved UI features allow efficient customization through a balance of automated label assignment and manual curation. Improved visualizations offer residue-level resolution of resulting targets and labeled fragments.

Enhanced Sensitivity for Deeper Library Generation

Dive deeper into your data than ever before! Enhancements to the Pulsar engine in SpectroDive 12 increase sensitivity, delivering 20% more precursor IDs over previous releases, enabling you to use more empirical data for panel generation.

Coupled with our built-in visualization tools, SpectroDive12 not only generates more IDs but also provides ease of use and straightforward validation.

SpectroDive is compatible with all leading targeted methods. It supports MRM/PRM workflows, SureQuant workflow and IM-based workflows, including prm-PASEF and FAIMS-PRM.

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