Leveraging Deep Proteome Profiling of Plasma-derived Extracellular Vesicles for Predictive Biomarker Discovery

Presenter: Yuehan Feng

The role of the Extracellular Vesicles (EVs) proteome as a crucial indicator in melanoma progression has long been recognized, but their potential as viable clinical biomarkers has remained relatively unexplored. Moreover, most proteomic techniques are incompatible with characterizing the EVs proteome due to its wide range of protein concentrations.

In a collaborative effort with the University of Zurich, the Université de Fribourg – Universität Freiburg, and Stanford University, we have successfully devised a workflow for isolating blood-derived exosomes and profiling their proteome content using our cutting-edge TrueDiscovery® platform.

Explore the comprehensive workflow for analyzing EVs as potential biomarkers in melanoma progression in our poster.