Biomarker Candidates for Tumors Identified from Deep‐Profiled Plasma Stem Predominantly from the Low Abundant Area - Publication - Biognosys

Biomarker Candidates for Tumors Identified from Deep‐Profiled Plasma Stem Predominantly from the Low Abundant Area – Publication

Marco Tognetti, Kamil Sklodowski, Sebastian Müller, Dominique Kamber, Jan Muntel, Roland Bruderer*, and Lukas Reiter*. Journal of Proteome Research

The plasma proteome has the potential to enable a holistic analysis of the health state of an individual. However, plasma biomarker discovery is difficult due to its high dynamic range and variability. Here, we present a novel automated analytical approach for deep plasma profiling and apply it to a 180-sample cohort of human plasma from lung, breast, colorectal, pancreatic, and prostate cancer.

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