Biomarker Candidates for Tumors Identified from Deep‐Profiled Plasma Stem Predominantly from the Low Abundant Area - Biognosys
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Biomarker Candidates for Tumors Identified from Deep‐Profiled Plasma Stem Predominantly from the Low Abundant Area

Marco Tognetti, Kamil Sklodowski, Sebastian Müller, Dominique Kamber, Jan Muntel, Roland Bruderer and Lukas Reiter

The plasma proteome has the potential to enable a holistic analysis of the health state of an individual. However, plasma biomarker discovery is difficult due to its high dynamic range and variability. Here, we present a novel automated analytical approach for deep plasma profiling and apply it to a 180-sample cohort of human plasma from lung, breast, colorectal, pancreatic, and prostate cancer.

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