TrueDiscovery Archives - Biognosys

Presenter: Yuehan Feng

Date: Tuesday, Sep 19, 2023, 11:45 AM – 1:00 PM
Session: PP03

Presenter: Ino Karemaker

Date: Monday, June 5
Topic area: Disease Biomarkers

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. Although immunotherapy has improved the treatment of NSCLC, a significant number of patients still fail to respond or develop resistance.

Our new White Paper explains how advances in mass spectrometry can now unlock the potential of the plasma proteome, uncovering actionable insights that are essential for biomarker discovery and targeted drug development.

Bruderer R, Muntel J, Müller S, Bernhardt OM, Gandhi T, Cominetti O, Macron C, Carayol J, Rinner O, Astrup A, Saris WHM, Hager J, Valsesia A, Dayon L, and Reiter L. Molecular & Cellular Proteomics.

We have established a robust capillary-flow DIA platform capable of measuring a large number of clinical samples in a fast and reproducible manner. The platform allowed the acquisition of 31 plasma proteomes per day, and a total of 1508 samples from the dietary intervention study DiOGenes measured on a single column. Our workflow revealed distinct biological reactions to weight loss and maintenance, and the comparison to independent studies showed the robustness for potential biomarker discovery.

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Poster MP 305 presented at ASMS 2022

Presenter: Christopher Below
Session: Ion Mobility: Applications I
Date: Monday, June 6

E-Poster #TP 005 presented at ASMS 2021

Presenter: Andrés Lanzós
Session: Biomarkers: Discovery
Date: Tuesday, November 2

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