Biofluid Biomarker Discovery Archives - Biognosys

Presenter: Yuehan Feng

Date: Tuesday, Sep 19, 2023, 11:45 AM – 1:00 PM
Session: PP03

Presenter: Ino Karemaker

Date: Monday, June 5
Topic area: Disease Biomarkers

Our new White Paper explains how advances in mass spectrometry can now unlock the potential of the plasma proteome, uncovering actionable insights that are essential for biomarker discovery and targeted drug development.

Poster MP 305 presented at ASMS 2022

Presenter: Christopher Below
Session: Ion Mobility: Applications I
Date: Monday, June 6

E-Poster #TP 005 presented at ASMS 2021

Presenter: Andrés Lanzós
Session: Biomarkers: Discovery
Date: Tuesday, November 2

The case study elaborates on the results of our pan-cancer proteomics study. We analyzed 180 plasma samples from lung, breast, colorectal, pancreatic, and prostate cancer using our next-generation TrueDiscovery™ platform to discover actionable biomarkers.

E-Poster #TP 025 presented at ASMS 2021

Presenter: Roland Bruderer
Session: Biomarkers: Discovery
Date: Tuesday, November 2

Presenter: Yuehan Feng

Authors: Marco Tognetti, Christoph Messner, Roland Bruderer, Dominique Kamber, Jacqueline Darrow, Alexandra Lewis, Jakob Vowinckel, Abhay Moghekar, Lukas Reiter, Yuehan Feng
In collaboration with with the Johns Hopkins University School of Medicine

Overview: Since the genome remains invariant throughout the lifespan, it is essential to understand the effects of aging on the proteome, as proteins play an integral role in all cellular functions and mediate the effects of epigenetic alterations. At the SfN Annual Meeting we presented a study in collaboration with Johns Hopkins University School of Medicine on proteomic profiling of biomarker candidates for Alzheimer’s Disease in plasma and CSF with our TrueDiscovery™ platform.

Download the poster to learn more about how the quantitative proteoform map is linked to healthy and pathological aging, providing a rich resource for therapeutic target discovery.

Presenter: Lukas Reiter
Date: November 7

The poster discusses how plasma samples were measured using Biognosys’ TrueDiscovery workflow. Due to the particular protein abundance distribution in human plasma substantial improvements in proteome depth could be achieved allowing to profile more than 4000 proteins using a single shot mass spectrometry workflow.

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