Biognosys' technology helps find potential protein biomarkers for spontaneous preterm birth

Researchers from NX Prenatal, the Women’s Hospital Boston, John Hopkins University School of Medicine and the University of Texas analyzed circulating microparticles from plasma samples of pregnant women with the aim of identifying biomarkers that allow the stratification of spontaneous preterm birth before clinical presentation.

According to the authors “the analysis of circulating microparticles in pregnancy is of revolutionary potential as it represents an in vivo ‘biopsy’ of active gestational tissues.” Using targeted proteomics methods and tools from Biognosys 132 proteins were individually assessed for ability to differentiate spontaneous preterm birth from term deliveries. Several statistically significant CMP associated protein biomarker candidates were identified.


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